Brain Health Insights

Does tattoo ink increase cancer risk?

What the latest science says and less risky ink options

The First Stem Cell Therapy for Parkinson's Is Here. What does it mean?

How Much Muscle Do You Need to Live Longer and Stay Cognitively Sharp?

Does the adult human brain make new neurons? (new study out in Nature)

Can Flickering Lights and Clicking Sounds Protect Your Brain from Alzheimer’s?

Reviewing the evidence for 40 Hz devices

Are We Actually Aging More Slowly Than Our Parents Did?

Low-Dose Lithium for Brain Health?

Addressing one of the questions people most frequently ask me

How to Decrease Your Late Stage Cancer Risk from 20% to 2%

Nootropic Properties of Nicotine (without the smoke).

Why I'm Still Bullish on This Molecule

The New York Times Called Galleri a Failed Test. I Think They Got It Wrong.

What's Leaching Into Your Beans?

The hidden cost of canned food

Your Genes Matter More Than You Were Told

A new paper in Science just overturned one of the most cited claims in longevity

BMI and Your Brain. What the Science Actually Says.

Observational studies, randomized trials, and genetic evidence tell a complicated story about BMI and dementia. Here’s how to make sense of it.

Carbs and the Brain. What the Science Actually Says.

Do you need carbs? Are they hurting you? And should you be wearing a CGM?

Transcranial Magnetic Stimulation for Brain Aging, Dementia, and Psychiatric Disorders

What the Science Actually Shows, Where the Field is Headed, and What You Can Do Now

Dietary Fat and the Brain: What the Science Actually Says About Dementia Prevention

Type of fat, cheese guide, fish guide, facts about EVOO

How Much Protein Does Your Brain Actually Need?

Making sense of conflicting data and a sample meal plan for APOE4 carriers

Dr. Goodenowe, Plasmalogens, and the Cholesterol “Scam”

What the evidence actually says about this popular supplement scientist

The Bredesen Clinical Trial for Alzheimer's Treatment (New Study)

A critical read of the paper and the evidence for the ReCODE protocol

Alcohol, Brain Health, and Longevity

Placing the good, the bad, and the uncertain, into context

Growth Hormone/IGF-1 Optimization, Brain Health, and Longevity

Why reversing somatopause should give you pause

The Science of VO2 Max and Dementia Prevention

Male Hormone Optimization for Brain Health, Sleep, and Longevity

Peptides for Cognitive Enhancement & Dementia Prevention

A review of popular peptides including GLP1-RAs, SS-31, BPC-157, and Cerebrolysin

How I dropped my NeuroAge by 1.2 years

What I've learned from my own personal brain biohacking journey

Exercise for Cognitive Sharpness and Dementia Prevention

What type and amount of exercise is the most beneficial

Do Cognitive Training Games Improve Brain Health?

Keto or Ket-no for brain health?

My take on what we know from the scientific literature

Your Brain Chooses Cleaning Over Focus When Sleep-Deprived (new study out of MIT)

mTOR: Genetic Variants, Rapamycin, Longevity, and Brain Health

The PCSK9 longevity gene- therapeutics, heart health, brain health, and supplements

Optimal cholesterol levels for longevity and brain health

Making sense of the wide range of opinions on ideal cholesterol levels

The biohacker mitochondrial enhancing peptide, SS-31, just received FDA approval

IL-6 genetic variants, levels, and longevity

The good, the bad, and what to do about it

The Top 25 Supplements for the Brain

MTHFR genetics, homocysteine levels, folic acid supplementation, and health

What it means for you if you have MTHFR genetic variants

CETP, longevity, and brain health

What we know about CETP levels, genetic variants, and therapeutics

IGF1R, longevity, and brain health

What we know about IGF1R levels, genetic variants, and therapeutics

FOXO3, longevity, and brain health

What we know about FOXO3 levels, genetic variants, and ways to increase its levels

Klotho, longevity, and brain health

What we know about Klotho levels, genetic variants, and therapeutics

Lion's Mane mushrooms and brain health

The scientific evidence behind eating or supplementing Lion's Mane

Reaction time training improves brain health and lowers dementia risk by ~30%

The evidence for and amount of reaction time training to optimize cognition

Magic mushrooms and longevity (new studies)

Contextualizing new studies that point to lifespan and healthspan extending properties of psilocybin mushrooms

APOE and Alzheimer's

Understanding the most common Alzheimer's risk gene and what to do about it

What is biological age?

Making sense of a term that scientists have quibbled over and has confused the public

Get a CLU

Biomarker testing for Clusterin (CLU) and a therapy targeting it for cognitive decline (new study)

The bidding war for buying 23andMe

What it says about the value of genomic data for therapeutic development in the age of AI

The NeuroAge Neuprint

The 9 pillars for optimal brain health

Beef tallow and brain health

The bad idea that seems to be sweeping the internet

Removing your blood, filtering it, and transfusing it back lowers your biological age (new study)

Therapeutic Plasma Exchange (TPE) shows promise for health benefits in a new study by researchers at the Buck

To D or not to D

I wade into the vitamin D supplementation debate in the wake of a new study showing that it may slow biological aging

The first Alzheimer's blood test is approved by the FDA

Contextualizing the new p-tau 217/ beta-amyloid 1-42 Alzheimer's test and what it and other commercially available tests mean for consumers

Parkinson's, Pesticides, and Proximity to Golf Courses

A new study showed that people who live within 3 miles of a golf course are at increased risk of Parkinson's Disease

Sleep and the brain

Why we need sleep and how to improve it

Omega-3 supplements reverse biological aging clocks (new study)

Steve Horvath and colleagues show that Omega-3s but not Vitamin D or exercise turn back 3 out of 4 epigenetic clocks tested

Chicken Cacciatore

A delicious protein and vegetable packed mediterranean recipe

Hormone Replacement Therapy (HRT) and the brain

What starting HRT taught me about the role of estrogen and progesterone in sleep, energy, and mood

A Statin for Alzheimer's?

The promise of WashU's new Alzheimer's prevention study in high-risk young people

Grace's Kale Salad

A delicious way to consume your greens

Microplastics and the brain

Yes, I spent last week revamping my food storage and cookware collection

Exercise releases "plant food" for your brain

What we know about exercise and BDNF

Are GLP-1RAs the first longevity drugs?

What we know so far from the scientific literature

Georgio's Greek Stew

Get your veg on with this delicious Greek version of ratatouille

Statins and Dementia Prevention

Friend or Foe?

How to reverse your brain aging

What we know from the scientific literature

Omega-3 Banana Walnut Chocolate Chip Bread Recipe

A delicious way to enhance your brain health

Why I founded NeuroAge Therapeutics

A personal journey in Alzheimer's prevention

Outlive- a review of the book and its science

Increasing Clinical Trial Success Rates

Better animal models, organoids, keeping organs alive after death, causal inference, and AI-driven human data mining

Longevity's "snake oil" problem.

What's gold, what's grift, and what are legitimate open scientific questions.

Of Ice and Fire

What we know about cold water swimming and sauna for health benefits

How old are you really?

The promise and caveats of "aging clock" tests to determine biological age.

Should you take metformin if you don't have diabetes?

How it works and the risk-benefit of taking it

What is a longevity gene?

And why you should care

Why lifespan extension is a good idea

(And how I came to study longevity)

Small case upticks in the Northeastern US, and B.A.2 sub-variants

Alzheimer's, Aduhelm, and the amyloid hypothesis.

Why the new Alzheimer's drug was approved by fast track by the US FDA when it shows no cognitive benefit for patients and the scientific history behind it.

The US won't have a BA.2 wave this spring, here's why.

You can safely ignore the New York Times and other publications saying otherwise.

Coming soon